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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Understanding Evidence Quality | How Hair Loss Companies Cheat Clinical Trials
By Perfect Hair Health Team
Sep 6, 2023

Understanding Evidence Quality | How Hair Loss Companies Cheat Clinical Trials

In this guide, we’ll expose how big-brand companies in the hair loss industry cheat their clinical study results – all so they can convince hair loss sufferers to buy products that probably won’t work for them. Due to a broad definition of “hair loss” and “hair growth&#...
Fluridil: A Topical That Regrows Hair, Without Side Effects? (Scientific Deep-Dive)
By Sarah King, PhD
Mar 6, 2023

Fluridil: A Topical That Regrows Hair, Without Side Effects? (Scientific Deep-Dive)

Fluridil (topilutamide) is a topical anti-androgen that may help reduce levels of testosterone and dihydrotestosterone in the scalp. Some users claim the drug regrows hair, doesn’t cause side effects, and doesn’t affect hormones elsewhere in the body. But is this actually true? To date, ...
Regrowth from Minoxidil: How Much Should I Expect?
By Perfect Hair Health Team
Feb 24, 2023

Regrowth from Minoxidil: How Much Should I Expect?

How much regrowth can we expect from minoxidil? As with any hair loss treatment, it depends on a number of factors: genetic variance in the SULT1A1 gene, the delivery method of minoxidil (oral vs. topical), the dosing amount and schedule, and if minoxidil is combined with interventions that might en...
How Does Minoxidil Work? 3 Hypotheses + Debates
By Perfect Hair Health Team
Feb 23, 2023

How Does Minoxidil Work? 3 Hypotheses + Debates

Despite decades of study and FDA approval, researchers still aren’t sure exactly how minoxidil regrows hair. Over the last few years, investigators have explored a number of hypothetical mechanisms ranging from vasodilation to prostaglandin modulation to anti-androgenic effects. In this articl...
How Often Do I Need To Apply Topical Finasteride?
By Perfect Hair Health Team
Feb 23, 2023

How Often Do I Need To Apply Topical Finasteride?

Is a single daily topical finasteride application enough to significantly reduce DHT levels and regrow hair? It depends on the dilution of topical finasteride, the application volume (in mL), the carrier ingredients, how long that topical finasteride is left on the scalp prior to washing it out, and...
How Often Do I Need To Take Oral Finasteride?
By Perfect Hair Health Team
Feb 22, 2023

How Often Do I Need To Take Oral Finasteride?

Oral finasteride is prescribed at 1 mg daily to treat androgenic alopecia (AGA). However, clinical studies suggest that doses as low as 0.2 mg daily can reduce levels of dihydrotestosterone (DHT) nearly the same as 1.0 mg daily doses, and improve hair counts similarly to 1 mg daily. But do these low...
How Long Does Finasteride Stay in Scalp Tissue?
By Perfect Hair Health Team
Feb 20, 2023

How Long Does Finasteride Stay in Scalp Tissue?

Finasteride is an FDA-approved hair loss treatment, with clinical studies showing that the drug lowers levels of the hormone dihydrotestosterone (DHT) by 60-70%, and in doing so, improves outcomes of androgenic alopecia (AGA) for 80-90% of the men who try to the drug. But how long do finasterideR...
How Long Does Finasteride Stay in the Bloodstream?
By Perfect Hair Health Team
Feb 17, 2023

How Long Does Finasteride Stay in the Bloodstream?

Oral finasteride is an excellent option for men wanting a ‘hands-free’ approach to hair maintenance. However, some men decide to temporarily or discontinue use of the drug to troubleshoot side effects, conceive, or even start donating blood. Under these circumstances, how long does finasteride stay ...
What’s the Best Dose of Finasteride for Hair Loss?
By Perfect Hair Health Team
Feb 16, 2023

What’s the Best Dose of Finasteride for Hair Loss?

The best daily dose of finasteride should strike the balance between minimizing drug exposure (and thereby side effect risks) while maximizing drug efficacy (and thereby hair regrowth). While the FDA has approved 1 mg daily doses of finasteride for androgenic alopecia, there’s also evidence th...
What Is Post-Finasteride Syndrome (PFS)? Is It Real? And What Is Its Prevalence?
By Perfect Hair Health Team
Feb 16, 2023

What Is Post-Finasteride Syndrome (PFS)? Is It Real? And What Is Its Prevalence?

Post-Finasteride Syndrome (PFS) is a term used to describe persistent sexual or cognitive side effects from finasteride, even months after quitting the medication. The existence of PFS is hotly debated amongst hair loss researchers, endocrinologists, and dermatologists. In this article, we’ll ...

Stop guessing which hair loss
treatments actually work

Instead, just read our cheat sheet

You’ll get the facts on nine “natural” and “conventional” hair loss treatments: how they work, how much hair they’ll regrow, their limitations, and what their marketers don’t want you know.