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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Cannabidiol (CBD) Increases Hair Counts By 246%? Not So Fast.
By Sarah King, PhD
Oct 11, 2024

Cannabidiol (CBD) Increases Hair Counts By 246%? Not So Fast.

CBD, a non-psychoactive compound from Cannabis sativa, is being explored for hair regrowth due to its anti-inflammatory, antioxidant, and circulation-boosting properties. Small studies on CBD topicals for androgenic alopecia (AGA) show hair count increases between 55% and 246% over six months. At a ...
Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type.
By Sarah King, PhD
Sep 27, 2024

Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type.

Creatine, a substance that supports energy production in the muscles and brain, is commonly used as a supplement to boost athletic performance. However, its potential link to hair loss has raised concerns, particularly due to its effect on dihydrotestosterone (DHT), a hormone associated with androge...
Can Progesterone Improve Hair Regrowth?
By Sarah King, PhD
Sep 18, 2024

Can Progesterone Improve Hair Regrowth?

Progesterone is a hormone that plays a vital role in female reproductive health. Deficiencies in progesterone have been linked to hair thinning, particularly in conditions like female pattern hair loss (FPHL) and postpartum telogen effluvium (PPTE). While natural progesterone seems to have 5-alpha-r...
CRABP2: Can This Gene Predict Regrowth From Retinoids?
By Ben Fletcher, PhD
Sep 10, 2024

CRABP2: Can This Gene Predict Regrowth From Retinoids?

The CRABP2 gene, which plays a role in retinoic acid metabolism, has been linked to hair health. Retinoic acid, a derivative of vitamin A, is known to influence hair growth, and some studies suggest CRABP2 may also be involved. However, the evidence connecting CRABP2 variants to hair loss and treatm...
BTD: Can This Gene Predict Regrowth From Biotin?
By Ben Fletcher, PhD
Sep 8, 2024

BTD: Can This Gene Predict Regrowth From Biotin?

The BTD gene, responsible for encoding the enzyme biotinidase, is crucial for biotin metabolism. Biotin, or vitamin B7, plays a significant role in hair health, and biotinidase deficiency—caused by BTD polymorphisms—can lead to hair loss conditions like alopecia. While some studies suggest that biot...
COL1A1: Can This Gene Predict Regrowth From Collagen Support?
By Ben Fletcher, PhD
Sep 4, 2024

COL1A1: Can This Gene Predict Regrowth From Collagen Support?

The COL1A1 gene, responsible for producing a key component of type 1 collagen, has been associated with hair growth and structure. Certain genetic variations in COL1A1 might affect the balance of collagen chains, potentially influencing hair loss and the response to treatments. However, the current ...
2dDR For Hair Loss: What Do We Know So Far About This Sugar?
By Sarah King, PhD
Sep 4, 2024

2dDR For Hair Loss: What Do We Know So Far About This Sugar?

2dDR Hair introduces hair care products featuring 2-deoxy-D-ribose (2dDR), a naturally occurring sugar, claiming it can support hair regrowth. While a recent mouse study shows favorable results, there is currently no clinical evidence in humans to support its effectiveness or safety. In fact, after ...
CYP19A1: Can This Gene Predict Regrowth From Hormone Therapy?
By Ben Fletcher, PhD
Sep 4, 2024

CYP19A1: Can This Gene Predict Regrowth From Hormone Therapy?

Can your genes predict the effectiveness of hormone therapy for hair loss? The CYP19A1 gene, which encodes the enzyme aromatase, has been linked to hair growth and hair loss, particularly in androgenetic alopecia (AGA). Some studies suggest that certain CYP19A1 variants might influence the effective...
ACE: Can This Gene Predict Regrowth From Treatments Targeting Blood Flow?
By Ben Fletcher, PhD
Aug 27, 2024

ACE: Can This Gene Predict Regrowth From Treatments Targeting Blood Flow?

This article explores the potential link between angiotensin-converting enzyme (ACE) activity and hair loss, particularly in the context of androgenic alopecia (AGA) and alopecia areata (AA). While ACE plays a crucial role in blood pressure regulation and vasoconstriction, there is limited evidence ...
NR3C1: Can This Gene Predict Responsiveness to Glucocorticoids?
By Sarah King, PhD
Aug 21, 2024

NR3C1: Can This Gene Predict Responsiveness to Glucocorticoids?

The NR3C1 gene codes for the glucocorticoid receptor, a key player in the regulation of metabolism, immune response, and stress adaptation. Variations in the NR3C1 gene, such as the rs6198 SNP, have been linked to differences in glucocorticoid sensitivity with some variants leading to increased expr...

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