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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Zinc Supplements For Hair Loss: A Hard Look Into The Science
By Sarah King, PhD
Apr 25, 2024

Zinc Supplements For Hair Loss: A Hard Look Into The Science

Zinc is a popular trace element found in hair growth supplements. Animal studies suggest that zinc is required for healthy hair cycling. Human studies suggest that zinc deficiencies can cause hair loss from telogen effluvium. One study found that zinc sulfate might help with non-descript hair loss i...
Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type.
By Sarah King, PhD
Sep 27, 2024

Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type.

Creatine, a substance that supports energy production in the muscles and brain, is commonly used as a supplement to boost athletic performance. However, its potential link to hair loss has raised concerns, particularly due to its effect on dihydrotestosterone (DHT), a hormone associated with androge...
BTD: Can This Gene Predict Regrowth From Biotin?
By Ben Fletcher, PhD
Sep 8, 2024

BTD: Can This Gene Predict Regrowth From Biotin?

The BTD gene, responsible for encoding the enzyme biotinidase, is crucial for biotin metabolism. Biotin, or vitamin B7, plays a significant role in hair health, and biotinidase deficiency—caused by BTD polymorphisms—can lead to hair loss conditions like alopecia. While some studies suggest that biot...
COL1A1: Can This Gene Predict Regrowth From Collagen Support?
By Ben Fletcher, PhD
Sep 4, 2024

COL1A1: Can This Gene Predict Regrowth From Collagen Support?

The COL1A1 gene, responsible for producing a key component of type 1 collagen, has been associated with hair growth and structure. Certain genetic variations in COL1A1 might affect the balance of collagen chains, potentially influencing hair loss and the response to treatments. However, the current ...
Green Tea: Is It An Effective Hair Loss Treatment?
By Sarah King, PhD
May 2, 2024

Green Tea: Is It An Effective Hair Loss Treatment?

Green tea extract contains epigallocatechin gallate (EGCG) and many other compounds that allegedly improve hair growth. On the one hand, in vitro studies suggest that EGCG might inhibit hair follicle damage. On the other hand, human studies do not yet exist showing that green tea – as a supplement o...
Inositol: A Sugar That Supports Hair Growth? | Clinical Study Analysis
By Sarah King, PhD
Apr 25, 2024

Inositol: A Sugar That Supports Hair Growth? | Clinical Study Analysis

Inositol (in the form of myo-inositol or D-chiro-inositol) is found in many hair growth supplements. Clinical studies suggest inositol might normalize androgen levels in women with polycystic ovarian syndrome (PCOS). For these reasons, marketers often claim inositol can help regrow hair for those wi...
Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data
By Sarah King, PhD
Apr 19, 2024

Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data

Petri dish (i.e., in vitro) studies suggest that turmeric and its active constituent, curcumin, might decrease cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and nuclear factor kappa beta (NF-κB). Since these pathways and proteins share pathologic overlap with certain hair loss di...
Amino Acids To Treat Hair Loss? A Small Literature Review
By Richard Clayton, PhD
Apr 19, 2024

Amino Acids To Treat Hair Loss? A Small Literature Review

Amino acids are biomolecules and the building blocks of proteins. Marketers often misappropriate petri dish, animal, and small-scale human studies to suggest that the amino acids lysine, arginine, proline, & thiamine might help treat hair loss. But is this supported by clinical studies on humans...
Vitamin C (Ascorbic Acid) For Hair Regrowth: Fact vs. Fiction
By Sarah King, PhD
Apr 19, 2024

Vitamin C (Ascorbic Acid) For Hair Regrowth: Fact vs. Fiction

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that is naturally present in citrus fruits. Because humans lack an enzyme called gulonolactone oxidase, vitamin C must be taken up through the diet. The majority of evidence concerning vitamin C and its potential for hair growth is f...
Reparex (For Grey Hair): Does It Really Reverse Greying? | Scientific Analysis
By Sarah King, PhD
Apr 19, 2024

Reparex (For Grey Hair): Does It Really Reverse Greying? | Scientific Analysis

Reparex’s Against Grey Hair claims to “restore hair color naturally from the inside out”. During our company investigation, we found discrepancies between Reparex’s marketing claims and the mechanisms governing the graying process. We also found duplicative before-after photo...

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